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If a spell or ability you control targets a creature an opponent controls with hexproof and Nowhere to Run leaves the battlefield while that spell or ability is on the stack, that creature becomes an illegal target for that spell or ability

2 Bloodthirsty Conqueror No Pain, No Gain 5 Mana Cost in Black Creature The only real issue with Bloodthirsty Conqueror is its mana cost, being an expensive card to play in a color with fewer ways to ramp

All it cares about is single targets, which also creates an opportunity to teach about targeting

With the alternate casting cost, it's a good way for a blue deck to set itself back permanently in the land race